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Potential drug discovery for COVID-19 treatment targeting Cathepsin L using a deep learning-based strategy
Cathepsin L (CTSL), a cysteine protease that can cleave and activate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, could be a promising therapeutic target for coronavirus disease 2019 (COVID-19). However, there is still no clinically available CTSL inhibitor that ca...
Autores principales: | Yang, Wei-Li, Li, Qi, Sun, Jing, Huat Tan, Sia, Tang, Yan-Hong, Zhao, Miao-Miao, Li, Yu-Yang, Cao, Xi, Zhao, Jin-Cun, Yang, Jin-Kui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110316/ https://www.ncbi.nlm.nih.gov/pubmed/35602976 http://dx.doi.org/10.1016/j.csbj.2022.05.023 |
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