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A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

Ribonucleotide reductase (RNR) is an essential enzyme that catalyzes the synthesis of DNA building blocks in virtually all living cells. NrdR, an RNR-specific repressor, controls the transcription of RNR genes and, often, its own, in most bacteria and some archaea. NrdR senses the concentration of n...

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Detalles Bibliográficos
Autores principales: Rozman Grinberg, Inna, Martínez-Carranza, Markel, Bimai, Ornella, Nouaïria, Ghada, Shahid, Saher, Lundin, Daniel, Logan, Derek T., Sjöberg, Britt-Marie, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110341/
https://www.ncbi.nlm.nih.gov/pubmed/35577776
http://dx.doi.org/10.1038/s41467-022-30328-1