Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists

Diacylglycerol (DAG) is a versatile lipid whose 1,2-sn-stereoisomer serves both as second messenger in signal transduction pathways that control vital cellular processes, and as metabolic precursor for downstream signaling lipids such as phosphatidic acid. Effector proteins translocate to available...

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Detalles Bibliográficos
Autores principales: Katti, Sachin S., Krieger, Inna V., Ann, Jihyae, Lee, Jeewoo, Sacchettini, James C., Igumenova, Tatyana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110374/
https://www.ncbi.nlm.nih.gov/pubmed/35577811
http://dx.doi.org/10.1038/s41467-022-30389-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110374/
https://www.ncbi.nlm.nih.gov/pubmed/35577811
http://dx.doi.org/10.1038/s41467-022-30389-2

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