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Efficient access to general α-tertiary amines via water-accelerated organocatalytic multicomponent allylation

A tetrasubstituted carbon atom connected by three sp(3) or sp(2)-carbons with single nitrogen, i.e., the α-tertiary amine (ATA) functional group, is an essential structure of diverse naturally occurring alkaloids and pharmaceuticals. The synthetic approach toward ATA structures is intricate, therefo...

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Detalles Bibliográficos
Autores principales: Goswami, Prithwish, Cho, Sung Yeon, Park, Jin Hyun, Kim, Woo Hee, Kim, Hyun Jin, Shin, Myoung Hyeon, Bae, Han Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110412/
https://www.ncbi.nlm.nih.gov/pubmed/35577799
http://dx.doi.org/10.1038/s41467-022-30281-z