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Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192

Epigenetics plays a critical role in regulating mesenchymal stem cells’ (MSCs) fate for tissue repair and regeneration. There is increasing evidence that the inhibition of histone deacetylase (HDAC) isoform 3 can enhance MSC osteogenesis. This study investigated the potential of using a selective HD...

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Detalles Bibliográficos
Autores principales: Man, Kenny, Joukhdar, Habib, Manz, Xue D., Brunet, Mathieu Y., Jiang, Lin-Hua, Rnjak-Kovacina, Jelena, Yang, Xuebin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110470/
https://www.ncbi.nlm.nih.gov/pubmed/35362831
http://dx.doi.org/10.1007/s00441-022-03613-0