Comparison of UGT1A1 Polymorphism as Guidance of Irinotecan Dose Escalation in RAS Wild-Type Metastatic Colorectal Cancer Patients Treated With Cetuximab or Bevacizumab Plus FOLFIRI as the First-Line Therapy

Uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) polymorphism plays a crucial role in the increased susceptibility and toxicity of patients to irinotecan. This retrospective, observational study compared the clinical outcomes and adverse events (AEs) in RAS wild-type metastatic colorectal ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Hsiang-Lin, Chen, Yen-Cheng, Yin, Tzu-Chieh, Su, Wei-Chih, Chen, Po-Jung, Chang, Tsung-Kun, Li, Ching-Chun, Huang, Ching-Wen, Wang, Jaw-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110692/
https://www.ncbi.nlm.nih.gov/pubmed/35177165
http://dx.doi.org/10.3727/096504022X16451187313084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110692/
https://www.ncbi.nlm.nih.gov/pubmed/35177165
http://dx.doi.org/10.3727/096504022X16451187313084

Ejemplares similares