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Suberoylanilide Hydroxamic Acid (SAHA) Treatment Reveals Crosstalk Among Proteome, Phosphoproteome, and Acetylome in Nasopharyngeal Carcinoma Cells

Suberoylanilide hydroxamic acid (SAHA), a famous histone deacetylase (HDAC) inhibitor, has been utilized in clinical treatment for cutaneous T-cell lymphoma. Previously, the mechanisms underlying SAHA anti-tumor activity mainly focused on acetylome. However, the characteristics of SAHA in terms of o...

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Detalles Bibliográficos
Autores principales: Huang, Huichao, Fu, Ying, Duan, Yankun, Zhang, Ye, Lu, Miaolong, Chen, Zhuchu, Li, Maoyu, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110868/
https://www.ncbi.nlm.nih.gov/pubmed/35591851
http://dx.doi.org/10.3389/fgene.2022.873840