The collectrin‐like part of the SARS‐CoV‐1 and ‐2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17

The transmembrane protease angiotensin converting enzyme 2 (ACE2) is a protective regulator within the renin angiotensin system and additionally represents the cellular receptor for SARS‐CoV. The release of soluble ACE2 (sACE2) from the cell surface is hence believed to be a crucial part of its (pat...

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Detalles Bibliográficos
Autores principales: Niehues, Rabea Victoria, Wozniak, Justyna, Wiersch, Florian, Lilienthal, Eva, Tacken, Nikola, Schumertl, Tim, Garbers, Christoph, Ludwig, Andreas, Düsterhöft, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111296/
https://www.ncbi.nlm.nih.gov/pubmed/35199397
http://dx.doi.org/10.1096/fj.202101521R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111296/
https://www.ncbi.nlm.nih.gov/pubmed/35199397
http://dx.doi.org/10.1096/fj.202101521R

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