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Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy

Background: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease caused by mutations in the dystrophin gene. Due to their phenotypic similarity to human patients, large animal models are invaluable tools for pre-clinical trials. The DE50-MD dog is a relatively new model of DMD, and ca...

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Detalles Bibliográficos
Autores principales: Riddell, Dominique O., Hildyard, John C. W., Harron, Rachel C. M., Wells, Dominic J., Piercy, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111359/
https://www.ncbi.nlm.nih.gov/pubmed/35600245
http://dx.doi.org/10.12688/wellcomeopenres.17398.2