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The effect of age on the magnitude and longevity of Th1‐directed CD4 T‐cell responses to SARS‐CoV‐2

Age is associated with changes in the immune system which increase the risk for severe COVID‐19. Here, we investigate SARS‐CoV‐2‐reactive CD4 T cells from individuals recovered from SARS‐CoV‐2 infection with mild COVID‐19 symptoms after 3, 6 and 9 months using incubation with SARS‐CoV‐2 S1, S2 and N...

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Detalles Bibliográficos
Autores principales: Nattrass, Ryan G., Krafft, Lisa, Zjablovskaja, Polina, Schuster, Marc, Kasmapour, Bahram, Sarisoy, Cem, Minich, Jessica, Bach, Elena, Streeck, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111694/
https://www.ncbi.nlm.nih.gov/pubmed/35396852
http://dx.doi.org/10.1111/imm.13475