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Zuo-Gui-Wan Aqueous Extract Ameliorates Glucocorticoid-Induced Spinal Osteoporosis of Rats by Regulating let-7f and Autophagy

OBJECTIVE: This study proposes to explore the protective effect of Zuo-Gui-Wan (ZGW) aqueous extract on spinal glucocorticoid-induced osteoporosis (GIOP) in vivo and in vitro, and the underlying mechanisms of ZGW in GIOP and osteogenic differentiation of bone marrow-derived mesenchymal stem cells (B...

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Detalles Bibliográficos
Autores principales: Shen, Gengyang, Shang, Qi, Zhang, Zhida, Zhao, Wenhua, Chen, Honglin, Mijiti, Ibrayinjan, Chen, Guifeng, Yu, Xiang, Yu, Fuyong, Zhang, Peng, He, Jiahui, Zhang, Xuelai, Tang, Jingjing, Cui, Jianchao, Liang, De, Zeng, Lingfeng, Ren, Hui, Jiang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111739/
https://www.ncbi.nlm.nih.gov/pubmed/35592785
http://dx.doi.org/10.3389/fendo.2022.878963