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Pramef12 enhances reprogramming into naïve iPS cells

Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by forced expression of the transcription factors Oct3/4, Klf4, Sox2, and c-Myc (OKSM). Somatic cell nuclear transfer can also be utilized to reprogram somatic cells into totipotent embryos, suggesting that factors present i...

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Detalles Bibliográficos
Autores principales: Haraguchi, Daiki, Nakamura, Toshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111934/
https://www.ncbi.nlm.nih.gov/pubmed/35592616
http://dx.doi.org/10.1016/j.bbrep.2022.101267