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Transcriptome and metabolome after porcine hemodynamic-directed CPR compared with standard CPR and sham controls

OBJECTIVE: The effect of cardiac arrest (CA) on cerebral transcriptomics and metabolomics is unknown. We previously demonstrated hemodynamic-directed CPR (HD-CPR) improves survival with favorable neurologic outcomes versus standard CPR (Std-CPR). We hypothesized HD-CPR would preserve the cerebral tr...

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Detalles Bibliográficos
Autores principales: Senthil, Kumaran, Hefti, Marco M., Singh, Larry N., Morgan, Ryan W., Mavroudis, Constantine D., Ko, Tiffany, Gaudio, Hunter, Nadkarni, Vinay M., Ehinger, Johannes, Berg, Robert A., Sutton, Robert M., McGowan, Francis X., Kilbaugh, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111986/
https://www.ncbi.nlm.nih.gov/pubmed/35592874
http://dx.doi.org/10.1016/j.resplu.2022.100243