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Micro-RNA-124-5p promotes insulin producing cell differentiation through regulating transcriptional factor NKX6.1

AIMS: Differentiating human embryonic stem cells into pancreatic β cells has been proposed as a practical approach to managing diabetes. There have been several protocols attempting to generate β-like cells or insulin-producing cells (IPCs), but their low efficiency is a common issue. The expression...

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Detalles Bibliográficos
Autores principales: Zhang, Xianjun, Shao, Shunzi, Zhao, Xijiang, Zhang, Meng, Wang, Jingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111988/
https://www.ncbi.nlm.nih.gov/pubmed/35592615
http://dx.doi.org/10.1016/j.bbrep.2022.101273