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Micro-RNA-124-5p promotes insulin producing cell differentiation through regulating transcriptional factor NKX6.1
AIMS: Differentiating human embryonic stem cells into pancreatic β cells has been proposed as a practical approach to managing diabetes. There have been several protocols attempting to generate β-like cells or insulin-producing cells (IPCs), but their low efficiency is a common issue. The expression...
Autores principales: | Zhang, Xianjun, Shao, Shunzi, Zhao, Xijiang, Zhang, Meng, Wang, Jingbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111988/ https://www.ncbi.nlm.nih.gov/pubmed/35592615 http://dx.doi.org/10.1016/j.bbrep.2022.101273 |
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