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Biochemical purification uncovers mammalian sterile 3 (MST3) as a new protein kinase for multifunctional protein kinases AMPK and SIK3

The AMP-activated protein kinase (AMPK) and AMPK-related kinase salt-inducible kinase 3 (SIK3) regulate many important biological processes ranging from metabolism to sleep. Liver kinase B1 is known to phosphorylate and activate both AMPK and SIK3, but the existence of other upstream kinases was unc...

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Detalles Bibliográficos
Autores principales: Liu, Yuxiang, Wang, Tao V., Cui, Yunfeng, Gao, Shengxian, Rao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112001/
https://www.ncbi.nlm.nih.gov/pubmed/35413286
http://dx.doi.org/10.1016/j.jbc.2022.101929