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Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice

BACKGROUND AND PURPOSE: Excess nutrient‐induced endothelial cell inflammation is a hallmark of high fat diet (HFD)‐induced metabolic syndrome. Pharmacological activation of the protein kinase AMP‐activated α1 (PRKAA1) also known as AMPKα1, shows its beneficial effects in many studies of cardiometabo...

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Detalles Bibliográficos
Autores principales: Yang, Qiuhua, Ma, Qian, Xu, Jiean, Liu, Zhiping, Mao, Xiaoxiao, Zhou, Yaqi, Cai, Yongfeng, Da, Qingen, Hong, Mei, Weintraub, Neal L., Fulton, David J., Belin de Chantemèle, Eric J., Huo, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112062/
https://www.ncbi.nlm.nih.gov/pubmed/34796475
http://dx.doi.org/10.1111/bph.15742