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The case for cancer-associated fibroblasts: essential elements in cancer drug discovery?

Although cancer-associated fibroblasts (CAFs) have gained increased attention for supporting cancer progression, current CAF-targeted therapeutic options are limited and failing in clinical trials. As the largest component of the tumor microenvironment (TME), CAFs alter the biochemical and physical...

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Detalles Bibliográficos
Autores principales: Brewer, Gabrielle, Fortier, Anne-Marie, Park, Morag, Moraes, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112234/
https://www.ncbi.nlm.nih.gov/pubmed/35600290
http://dx.doi.org/10.4155/fdd-2021-0004