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The case for cancer-associated fibroblasts: essential elements in cancer drug discovery?
Although cancer-associated fibroblasts (CAFs) have gained increased attention for supporting cancer progression, current CAF-targeted therapeutic options are limited and failing in clinical trials. As the largest component of the tumor microenvironment (TME), CAFs alter the biochemical and physical...
Autores principales: | Brewer, Gabrielle, Fortier, Anne-Marie, Park, Morag, Moraes, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Newlands Press Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112234/ https://www.ncbi.nlm.nih.gov/pubmed/35600290 http://dx.doi.org/10.4155/fdd-2021-0004 |
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