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Multitargeted anti-infective drugs: resilience to resistance in the antimicrobial resistance era

The standard drug discovery paradigm of single molecule – single biological target – single biological effect is perhaps particularly unsuitable for anti-infective drug discovery. This is due to the rapid evolution of resistance likely to be observed with single target drugs. Multitargeted anti-infe...

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Detalles Bibliográficos
Autores principales: Suckling, Colin J, Hunter, Iain S, Scott, Fraser J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112235/
https://www.ncbi.nlm.nih.gov/pubmed/35600289
http://dx.doi.org/10.4155/fdd-2022-0001