Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa

[Image: see text] Antivirulence therapy has become a widely applicable method for fighting infections caused by multidrug-resistant bacteria. Among the many virulence factors produced by the Gram-negative bacterium Pseudomonas aeruginosa, elastase (LasB) stands out as an important target as it plays...

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Detalles Bibliográficos
Autores principales: Kaya, Cansu, Walter, Isabell, Alhayek, Alaa, Shafiei, Roya, Jézéquel, Gwenaëlle, Andreas, Anastasia, Konstantinović, Jelena, Schönauer, Esther, Sikandar, Asfandyar, Haupenthal, Jörg, Müller, Rolf, Brandstetter, Hans, Hartmann, Rolf W., Hirsch, Anna K.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112332/
https://www.ncbi.nlm.nih.gov/pubmed/35451824
http://dx.doi.org/10.1021/acsinfecdis.1c00628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112332/
https://www.ncbi.nlm.nih.gov/pubmed/35451824
http://dx.doi.org/10.1021/acsinfecdis.1c00628

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