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Environmentally Responsible and Cost-Effective Synthesis of the Antimalarial Drug Pyronaridine
[Image: see text] Two routes to the antimalarial drug Pyronaridine are described. The first is a linear sequence that includes a two-step, one-pot transformation in an aqueous surfactant medium, leading to an overall yield of 87%. Alternatively, a convergent route utilizes a telescoped three-step se...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112334/ https://www.ncbi.nlm.nih.gov/pubmed/35504038 http://dx.doi.org/10.1021/acs.orglett.2c00944 |