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Identifying common transcriptome signatures of cancer by interpreting deep learning models

BACKGROUND: Cancer is a set of diseases characterized by unchecked cell proliferation and invasion of surrounding tissues. The many genes that have been genetically associated with cancer or shown to directly contribute to oncogenesis vary widely between tumor types, but common gene signatures that...

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Detalles Bibliográficos
Autores principales: Jha, Anupama, Quesnel-Vallières, Mathieu, Wang, David, Thomas-Tikhonenko, Andrei, Lynch, Kristen W, Barash, Yoseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112525/
https://www.ncbi.nlm.nih.gov/pubmed/35581644
http://dx.doi.org/10.1186/s13059-022-02681-3