Direct bone marrow injection of human bone marrow-derived stromal cells into mouse femurs results in greater prostate cancer PC-3 cell proliferation, but not specifically proliferation within the injected femurs

BACKGROUND: While prostate cancer (PCa) cells most often metastasize to bone in men, species-specific differences between human and mouse bone marrow mean that this pattern is not faithfully replicated in mice. Herein we evaluated the impact of partially humanizing mouse bone marrow with human bone...

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Detalles Bibliográficos
Autores principales: Nowlan, Bianca, Williams, Elizabeth D., Doran, Michael Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112579/
https://www.ncbi.nlm.nih.gov/pubmed/35581599
http://dx.doi.org/10.1186/s12885-022-09430-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112579/
https://www.ncbi.nlm.nih.gov/pubmed/35581599
http://dx.doi.org/10.1186/s12885-022-09430-6

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