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Chidamide and apatinib are therapeutically synergistic in acute myeloid leukemia stem and progenitor cells

BACKGROUND: Leukemia stem cells (LSCs) are responsible for the initiation and perpetuation of acute myeloid leukemia (AML), and also represent leukemia relapse reservoirs with limited therapeutic approaches. Thus, additional treatment strategies are medical unmet needs to eliminate LSCs. METHODS: Ce...

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Detalles Bibliográficos
Autores principales: Zhao, Haijun, Jiang, Yuelong, Lin, Fusheng, Zhong, Mengya, Tan, Jinshui, Zhou, Yong, Liu, Long, Li, Guowei, Deng, Manman, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112613/
https://www.ncbi.nlm.nih.gov/pubmed/35581670
http://dx.doi.org/10.1186/s40164-022-00282-1