The need for increased pragmatism in cardiovascular clinical trials

The majority of cardiovascular randomized controlled trials (RCTs) test interventions in selected patient populations under explicitly protocol-defined settings. Although these ‘explanatory’ trial designs optimize conditions to test the efficacy and safety of an intervention, they limit the generali...

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Detalles Bibliográficos
Autores principales: Usman, Muhammad Shariq, Van Spall, Harriette G. C., Greene, Stephen J., Pandey, Ambarish, McGuire, Darren K., Ali, Ziad A., Mentz, Robert J., Fonarow, Gregg C., Spertus, John A., Anker, Stefan D., Butler, Javed, James, Stefan K., Khan, Muhammad Shahzeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112643/
https://www.ncbi.nlm.nih.gov/pubmed/35581337
http://dx.doi.org/10.1038/s41569-022-00705-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112643/
https://www.ncbi.nlm.nih.gov/pubmed/35581337
http://dx.doi.org/10.1038/s41569-022-00705-w

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