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Fast and accurate estimation of multidimensional site frequency spectra from low-coverage high-throughput sequencing data
BACKGROUND: The site frequency spectrum summarizes the distribution of allele frequencies throughout the genome, and it is widely used as a summary statistic to infer demographic parameters and to detect signals of natural selection. The use of high-throughput low-coverage DNA sequencing data can le...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112775/ https://www.ncbi.nlm.nih.gov/pubmed/35579549 http://dx.doi.org/10.1093/gigascience/giac032 |