Cargando…

Fast and accurate estimation of multidimensional site frequency spectra from low-coverage high-throughput sequencing data

BACKGROUND: The site frequency spectrum summarizes the distribution of allele frequencies throughout the genome, and it is widely used as a summary statistic to infer demographic parameters and to detect signals of natural selection. The use of high-throughput low-coverage DNA sequencing data can le...

Descripción completa

Detalles Bibliográficos
Autores principales: Mas-Sandoval, Alex, Pope, Nathaniel S, Nielsen, Knud Nor, Altinkaya, Isin, Fumagalli, Matteo, Korneliussen, Thorfinn Sand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112775/
https://www.ncbi.nlm.nih.gov/pubmed/35579549
http://dx.doi.org/10.1093/gigascience/giac032