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Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence In Vitro

The integrase strand transfer inhibitor (INSTI)-based regimens bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF), dolutegravir (DTG)+FTC/TAF, DTG/lamivudine (3TC), and DTG/rilpivirine (RPV) are all approved for treatment of HIV-infected patients, with various limitations. Here, time to i...

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Detalles Bibliográficos
Autores principales: Acosta, Rima K., D’Antoni, Michelle L., Mulato, Andrew, Yant, Stephen R., Cihlar, Tomas, White, Kirsten L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112893/
https://www.ncbi.nlm.nih.gov/pubmed/35389236
http://dx.doi.org/10.1128/aac.02038-21