Pharmacokinetics of Oral Tebipenem Pivoxil Hydrobromide in Subjects with Various Degrees of Renal Impairment

Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an oral carbapenem prodrug antimicrobial agent with broad-spectrum activity that includes multidrug-resistant (MDR) Enterobacterales. This study evaluated the safety, tolerability, and pharmacokinetics of TBP-PI-HBr in healthy subjects with normal renal...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Gina, Rodvold, Keith A., Gupta, Vipul K., Bruss, Jon, Gasink, Leanne, Bajraktari, Floni, Lei, Yang, Jain, Akash, Srivastava, Praveen, Talley, Angela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112917/
https://www.ncbi.nlm.nih.gov/pubmed/35420493
http://dx.doi.org/10.1128/aac.02407-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112917/
https://www.ncbi.nlm.nih.gov/pubmed/35420493
http://dx.doi.org/10.1128/aac.02407-21

Ejemplares similares