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Population Pharmacokinetics of Antimalarial Naphthoquine in Combination with Artemisinin in Tanzanian Children and Adults: Dose Optimization

The combination antimalarial therapy of artemisinin-naphthoquine (ART-NQ) was developed as a single-dose therapy, aiming to improve adherence relative to the multiday schedules of other artemisinin combination therapies. The pharmacokinetics of ART-NQ has not been well characterized, especially in c...

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Detalles Bibliográficos
Autores principales: Ali, Ali Mohamed, Gausi, Kamunkhwala, Jongo, Said A., Kassim, Kamaka R., Mkindi, Catherine, Simon, Beatus, Mtoro, Ali T., Juma, Omar A., Lweno, Omar N., Gwandu, Conrad H., Bakari, Bakari M., Mbaga, Thabiti A., Milando, Florence A., Hamad, Ali, Shekalaghe, Seif A., Abdulla, Salim, Denti, Paolo, Penny, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112936/
https://www.ncbi.nlm.nih.gov/pubmed/35465706
http://dx.doi.org/10.1128/aac.01696-21