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Leaks in the Pipeline: a Failure Analysis of Gram-Negative Antibiotic Development from 2010 to 2020

The World Health Organization (WHO) has warned that our current arsenal of antibiotics is not innovative enough to face impending infectious diseases, especially those caused by multidrug-resistant Gram-negative pathogens. Although the current preclinical pipeline is well stocked with novel candidat...

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Detalles Bibliográficos
Autores principales: Prasad, Neha K., Seiple, Ian B., Cirz, Ryan T., Rosenberg, Oren S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112940/
https://www.ncbi.nlm.nih.gov/pubmed/35471042
http://dx.doi.org/10.1128/aac.00054-22