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Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage

BACKGROUND: Cerebrospinal fluid (CSF) neurofilament light chain (NfL) reflects neuro-axonal damage and is increasingly used to evaluate disease progression across neurological conditions including Alzheimer disease (AD). However, it is unknown how NfL relates to specific types of brain tissue. We so...

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Detalles Bibliográficos
Autores principales: Meeker, Karin L., Butt, Omar H., Gordon, Brian A., Fagan, Anne M., Schindler, Suzanne E., Morris, John C., Benzinger, Tammie L.S., Ances, Beau M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112943/
https://www.ncbi.nlm.nih.gov/pubmed/35167933
http://dx.doi.org/10.1016/j.nbd.2022.105662