Cargando…
Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage
BACKGROUND: Cerebrospinal fluid (CSF) neurofilament light chain (NfL) reflects neuro-axonal damage and is increasingly used to evaluate disease progression across neurological conditions including Alzheimer disease (AD). However, it is unknown how NfL relates to specific types of brain tissue. We so...
Autores principales: | Meeker, Karin L., Butt, Omar H., Gordon, Brian A., Fagan, Anne M., Schindler, Suzanne E., Morris, John C., Benzinger, Tammie L.S., Ances, Beau M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112943/ https://www.ncbi.nlm.nih.gov/pubmed/35167933 http://dx.doi.org/10.1016/j.nbd.2022.105662 |
Ejemplares similares
-
Comparing Tau PET Visual Interpretation with Tau PET Quantification, Cerebrospinal Fluid Biomarkers, and Longitudinal Clinical Assessment
por: Chen, Charles D., et al.
Publicado: (2023) -
A map of neurofilament light chain species in brain and cerebrospinal fluid
and alterations in Alzheimer’s disease
por: Budelier, Melissa M., et al.
Publicado: (2022) -
Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease
por: Wang, Qing, et al.
Publicado: (2019) -
Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease
por: Schultz, Stephanie A., et al.
Publicado: (2020) -
The Spatial Patterns and Determinants of Cerebrospinal Fluid Circulation in the Human Brain
por: Nazeri, Arash, et al.
Publicado: (2023)