Transmembrane Protease Serine 2 Proteolytic Cleavage of the SARS-CoV-2 Spike Protein: A Mechanistic Quantum Mechanics/Molecular Mechanics Study to Inspire the Design of New Drugs To Fight the COVID-19 Pandemic

[Image: see text] Despite the development of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, there is an urgent need for efficient drugs to treat infected patients. An attractive drug target is the human transmembrane protease serine 2 (TMPRSS2) because of it...

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Detalles Bibliográficos
Autores principales: Teixeira, Luís M. C., Coimbra, João T. S., Ramos, Maria João, Fernandes, Pedro Alexandrino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113003/
https://www.ncbi.nlm.nih.gov/pubmed/35549216
http://dx.doi.org/10.1021/acs.jcim.1c01561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113003/
https://www.ncbi.nlm.nih.gov/pubmed/35549216
http://dx.doi.org/10.1021/acs.jcim.1c01561

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