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SARS-CoV-2 Delta Variant Decreases Nanobody Binding and ACE2 Blocking Effectivity

[Image: see text] The Delta variant spreads more rapidly than previous variants of SARS-CoV-2. This variant comprises several mutations on the receptor-binding domain (RBD(Delta)) of its spike glycoprotein, which binds to the peptidase domain (PD) of angiotensin-converting enzyme 2 (ACE2) receptors...

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Detalles Bibliográficos
Autores principales: Golcuk, Mert, Hacisuleyman, Aysima, Yilmaz, Sema Zeynep, Taka, Elhan, Yildiz, Ahmet, Gur, Mert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113008/
https://www.ncbi.nlm.nih.gov/pubmed/35533364
http://dx.doi.org/10.1021/acs.jcim.1c01523