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Inhibition of the BMP pathway prevents development of Barrett’s-associated adenocarcinoma in a surgical rat model

INTRODUCTION: Esophageal adenocarcinoma (EAC) is an aggressive cancer, associated with reflux esophagitis and intestinal metaplasia (IM). One underlying biological mechanism, which possibly drives the development of EAC, is the dysregulated expression of Bone Morphogenetic Proteins (BMPs). AIM: To i...

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Detalles Bibliográficos
Autores principales: Westra, Wytske M, Straub, Danielle, Milano, Francesca, Buttar, Navtej S, Wang, Kenneth K, Krishnadath, Kausilia K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113020/
https://www.ncbi.nlm.nih.gov/pubmed/34718471
http://dx.doi.org/10.1093/dote/doab072