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Inhibition of the BMP pathway prevents development of Barrett’s-associated adenocarcinoma in a surgical rat model
INTRODUCTION: Esophageal adenocarcinoma (EAC) is an aggressive cancer, associated with reflux esophagitis and intestinal metaplasia (IM). One underlying biological mechanism, which possibly drives the development of EAC, is the dysregulated expression of Bone Morphogenetic Proteins (BMPs). AIM: To i...
Autores principales: | Westra, Wytske M, Straub, Danielle, Milano, Francesca, Buttar, Navtej S, Wang, Kenneth K, Krishnadath, Kausilia K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113020/ https://www.ncbi.nlm.nih.gov/pubmed/34718471 http://dx.doi.org/10.1093/dote/doab072 |
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