CYP21A2 Gene Expression in a Humanized 21-Hydroxylase Mouse Model Does Not Affect Adrenocortical Morphology and Function

Steroid 21-hydroxylase is an enzyme of the steroid pathway that is involved in the biosynthesis of cortisol and aldosterone by hydroxylation of 17α-hydroxyprogesterone and progesterone at the C21 position. Mutations in CYP21A2, the gene encoding 21-hydroxylase, cause the most frequent form of the au...

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Detalles Bibliográficos
Autores principales: Schubert, Tina, Reisch, Nicole, Naumann, Ronald, Reichardt, Ilka, Landgraf, Dana, Quitter, Friederike, Thirumalasetty, Shamini Ramkumar, Heninger, Anne-Kristin, Sarov, Mihail, Peitzsch, Mirko, Huebner, Angela, Koehler, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113096/
https://www.ncbi.nlm.nih.gov/pubmed/35592511
http://dx.doi.org/10.1210/jendso/bvac062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113096/
https://www.ncbi.nlm.nih.gov/pubmed/35592511
http://dx.doi.org/10.1210/jendso/bvac062

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