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CYP21A2 Gene Expression in a Humanized 21-Hydroxylase Mouse Model Does Not Affect Adrenocortical Morphology and Function
Steroid 21-hydroxylase is an enzyme of the steroid pathway that is involved in the biosynthesis of cortisol and aldosterone by hydroxylation of 17α-hydroxyprogesterone and progesterone at the C21 position. Mutations in CYP21A2, the gene encoding 21-hydroxylase, cause the most frequent form of the au...
Autores principales: | Schubert, Tina, Reisch, Nicole, Naumann, Ronald, Reichardt, Ilka, Landgraf, Dana, Quitter, Friederike, Thirumalasetty, Shamini Ramkumar, Heninger, Anne-Kristin, Sarov, Mihail, Peitzsch, Mirko, Huebner, Angela, Koehler, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113096/ https://www.ncbi.nlm.nih.gov/pubmed/35592511 http://dx.doi.org/10.1210/jendso/bvac062 |
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