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A Genetic Bottleneck of Mitochondrial DNA During Human Lymphocyte Development

Mitochondria are essential organelles in eukaryotic cells that provide critical support for energetic and metabolic homeostasis. Although the elimination of pathogenic mitochondrial DNA (mtDNA) mutations in somatic cells has been observed, the mechanisms to maintain proper functions despite their mt...

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Detalles Bibliográficos
Autores principales: Tang, Zhongjie, Lu, Zhaolian, Chen, Baizhen, Zhang, Weixing, Chang, Howard Y., Hu, Zheng, Xu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113143/
https://www.ncbi.nlm.nih.gov/pubmed/35482398
http://dx.doi.org/10.1093/molbev/msac090