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A Genetic Bottleneck of Mitochondrial DNA During Human Lymphocyte Development
Mitochondria are essential organelles in eukaryotic cells that provide critical support for energetic and metabolic homeostasis. Although the elimination of pathogenic mitochondrial DNA (mtDNA) mutations in somatic cells has been observed, the mechanisms to maintain proper functions despite their mt...
Autores principales: | Tang, Zhongjie, Lu, Zhaolian, Chen, Baizhen, Zhang, Weixing, Chang, Howard Y., Hu, Zheng, Xu, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113143/ https://www.ncbi.nlm.nih.gov/pubmed/35482398 http://dx.doi.org/10.1093/molbev/msac090 |
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