Docking domain-mediated subunit interactions in natural product megasynth(et)ases

Polyketide synthase (PKS) and non-ribosomal peptide synthetase (NRPS) multienzymes produce numerous high value metabolites. The protein subunits which constitute these megasynth(et)ases must undergo ordered self-assembly to ensure correct organisation of catalytic domains for the biosynthesis of a g...

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Detalles Bibliográficos
Autores principales: Smith, Helen G, Beech, Matthew J, Lewandowski, Józef R, Challis, Gregory L, Jenner, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Natural Products
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113145/
https://www.ncbi.nlm.nih.gov/pubmed/33640957
http://dx.doi.org/10.1093/jimb/kuab018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113145/
https://www.ncbi.nlm.nih.gov/pubmed/33640957
http://dx.doi.org/10.1093/jimb/kuab018

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