Proteomic Alterations and Novel Markers of Neurotoxic Reactive Astrocytes in Human Induced Pluripotent Stem Cell Models

Astrocytes respond to injury, infection, and inflammation in the central nervous system by acquiring reactive states in which they may become dysfunctional and contribute to disease pathology. A sub-state of reactive astrocytes induced by proinflammatory factors TNF, IL-1α, and C1q (“TIC”) has been...

Descripción completa

Detalles Bibliográficos
Autores principales: Labib, David, Wang, Zhen, Prakash, Priya, Zimmer, Matthew, Smith, Matthew D., Frazel, Paul W., Barbar, Lilianne, Sapar, Maria L., Calabresi, Peter A., Peng, Junmin, Liddelow, Shane A., Fossati, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113221/
https://www.ncbi.nlm.nih.gov/pubmed/35592112
http://dx.doi.org/10.3389/fnmol.2022.870085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113221/
https://www.ncbi.nlm.nih.gov/pubmed/35592112
http://dx.doi.org/10.3389/fnmol.2022.870085

Ejemplares similares