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Xer recombination for the automatic deletion of selectable marker genes from plasmids in enteric bacteria
Antibiotic resistance genes are widely used to select bacteria transformed with plasmids and to prevent plasmid loss from cultures, yet antibiotics represent contaminants in the biopharmaceutical manufacturing process, and retaining antibiotic resistance genes in vaccines and biological therapies is...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113270/ https://www.ncbi.nlm.nih.gov/pubmed/35601876 http://dx.doi.org/10.1093/synbio/ysac005 |