Airpart: interpretable statistical models for analyzing allelic imbalance in single-cell datasets

MOTIVATION: Allelic expression analysis aids in detection of cis-regulatory mechanisms of genetic variation, which produce allelic imbalance (AI) in heterozygotes. Measuring AI in bulk data lacking time or spatial resolution has the limitation that cell-type-specific (CTS), spatial- or time-dependen...

Descripción completa

Detalles Bibliográficos
Autores principales: Mu, Wancen, Sarkar, Hirak, Srivastava, Avi, Choi, Kwangbom, Patro, Rob, Love, Michael I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113279/
https://www.ncbi.nlm.nih.gov/pubmed/35561168
http://dx.doi.org/10.1093/bioinformatics/btac212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113279/
https://www.ncbi.nlm.nih.gov/pubmed/35561168
http://dx.doi.org/10.1093/bioinformatics/btac212

Ejemplares similares