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Airpart: interpretable statistical models for analyzing allelic imbalance in single-cell datasets

MOTIVATION: Allelic expression analysis aids in detection of cis-regulatory mechanisms of genetic variation, which produce allelic imbalance (AI) in heterozygotes. Measuring AI in bulk data lacking time or spatial resolution has the limitation that cell-type-specific (CTS), spatial- or time-dependen...

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Detalles Bibliográficos
Autores principales:	Mu, Wancen, Sarkar, Hirak, Srivastava, Avi, Choi, Kwangbom, Patro, Rob, Love, Michael I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113279/ https://www.ncbi.nlm.nih.gov/pubmed/35561168 http://dx.doi.org/10.1093/bioinformatics/btac212

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