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Deep learning identifies and quantifies recombination hotspot determinants

MOTIVATION: Recombination is one of the essential genetic processes for sexually reproducing organisms, which can happen more frequently in some regions, called recombination hotspots. Although several factors, such as PRDM9 binding motifs, are known to be related to the hotspots, their contribution...

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Detalles Bibliográficos
Autores principales: Li, Yu, Chen, Siyuan, Rapakoulia, Trisevgeni, Kuwahara, Hiroyuki, Yip, Kevin Y, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113300/
https://www.ncbi.nlm.nih.gov/pubmed/35561158
http://dx.doi.org/10.1093/bioinformatics/btac234