Cargando…
Deep learning identifies and quantifies recombination hotspot determinants
MOTIVATION: Recombination is one of the essential genetic processes for sexually reproducing organisms, which can happen more frequently in some regions, called recombination hotspots. Although several factors, such as PRDM9 binding motifs, are known to be related to the hotspots, their contribution...
Autores principales: | Li, Yu, Chen, Siyuan, Rapakoulia, Trisevgeni, Kuwahara, Hiroyuki, Yip, Kevin Y, Gao, Xin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113300/ https://www.ncbi.nlm.nih.gov/pubmed/35561158 http://dx.doi.org/10.1093/bioinformatics/btac234 |
Ejemplares similares
-
CENTRE: a gradient boosting algorithm for Cell-type-specific ENhancer-Target pREdiction
por: Rapakoulia, Trisevgeni, et al.
Publicado: (2023) -
Genome-scale regression analysis reveals a linear relationship for promoters and enhancers after combinatorial drug treatment
por: Rapakoulia, Trisevgeni, et al.
Publicado: (2017) -
Unexpected DNA context-dependence identifies a new determinant of Chi recombination hotspots
por: Taylor, Andrew F., et al.
Publicado: (2016) -
hotspot: software to support sperm-typing for investigating recombination hotspots
por: Odenthal-Hesse, Linda, et al.
Publicado: (2016) -
Hotspots for Initiation of Meiotic Recombination
por: Tock, Andrew J., et al.
Publicado: (2018)