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Aromatase Inhibition Eliminates Sexual Receptivity Without Enhancing Weight Gain in Ovariectomized Marmoset Monkeys

CONTEXT: Ovarian estradiol supports female sexual behavior and metabolic function. While ovariectomy (OVX) in rodents abolishes sexual behavior and enables obesity, OVX in nonhuman primates decreases, but does not abolish, sexual behavior, and inconsistently alters weight gain. OBJECTIVE: We hypothe...

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Detalles Bibliográficos
Autores principales: Kraynak, Marissa, Willging, Molly M, Kuehlmann, Alex L, Kapoor, Amita A, Flowers, Matthew T, Colman, Ricki J, Levine, Jon E, Abbott, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113444/
https://www.ncbi.nlm.nih.gov/pubmed/35592515
http://dx.doi.org/10.1210/jendso/bvac063