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Use of a Contained Mycobacterium tuberculosis Mouse Infection Model to Predict Active Disease and Containment in Humans

Previous studies have identified whole-blood transcriptional risk and disease signatures for tuberculosis; however, several lines of evidence suggest that these signatures primarily reflect bacterial burden, which increases before symptomatic disease. We found that the peripheral blood transcriptome...

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Detalles Bibliográficos
Autores principales: Duffy, Fergal J, Olson, Gregory S, Gold, Elizabeth S, Jahn, Ana, Aderem, Alan, Aitchison, John D, Rothchild, Alissa C, Diercks, Alan H, Nemeth, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113476/
https://www.ncbi.nlm.nih.gov/pubmed/33693706
http://dx.doi.org/10.1093/infdis/jiab130